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Targeting of an inflammation-resolving peptide to injured blood vessels slows harmful steps in the progression of atherosclerosis.
Microfluidic technology from Harvard removes a broad range of pathogens from blood.
Nanoparticle cores could allow activation of endogenous gene expression using synthetic constructs in living organisms.
While not exactly brain-like, the David Kaplan group's 3D neuronal culture system represents an important advance because its mechanical stability supports long-term survival.
New screening method could identify the first disease-modifying drugs for multiple sclerosis.
Local delivery of a viral vector containing a transcription factor gene induces temporary endogenous pacemaker function in pigs.
Sonic vibrations can induce cells to form complex patterns, which could be useful in creating engineered tissues.
Polymeric nanoparticles coated with activated platelet-binding peptides developed previously by Erin Lavik's lab show promise for treating combat and accident injuries.
Albumin nanoparticles may selectively target neutrophils, which could lead to novel anti-inflammatory therapies.
Hypoxia can be detected up to one month after injection of a depot MRI agent, which could inform cancer treatment decisions.
Combining light-responsive proteins with transplantation of stem cell-derived neurons overcomes the challenges of each approach.
Novel strategy incorporating a biocompatible metal catalyst promises tumor-specific activation of 5-fluorouracil.
New capabilities for a cutting-edge in vivo imaging method: activatable photoacoustic contrast agent
In a research field-hopping advance, Jianghong Rao's lab finds that semiconducting polymer nanoparticles yield greater photoacoustic imaging contrast than previously studied materials.
Major advance in tumor-specific pH-activated fluorescent imaging by Jinming Gao's group in Nature Materials.
Biomimetic strategy enables most effective nanoparticle formulation for oral delivery of insulin to date.
Polymers without inherent molecular recognition abilities selectively recognize small molecules when adsorbed to carbon nanotubes.
Most drug-carrying nanoparticles are created by mixing drugs with lipids or polymers in complex mixtures of organic and aqueous solutions to create nanostructures (vesicles or polymer networks)...
Uhrich and Moghe’s breakthrough stemmed from their recognition that the low efficacy of small molecule blockers of the oxidized LDL receptor likely resulted from the fact that the receptor is...